Endoscopy is a widely used clinical procedure for the early detection of cancers in hollow-organs such as oesophagus, stomach, and colon. Computer-assisted methods for accurate and temporally consistent localisation and segmentation of diseased region-of-interests enable precise quantification and mapping of lesions from clinical endoscopy videos which is critical for monitoring and surgical planning. Innovations have the potential to improve current medical practices and refine healthcare systems worldwide.